Darlene McCord - Research on Anti-Aging
As the body ages it reproduces new cells less rapidly.1 As a result the body is less able to repair itself against disease, fatigue, and infection. In the past few decades myriads of research has been done about possible agents that can possibly alleviate and decrease the effects of aging.
Darlene McCord Anti-Aging Tips
Oxidative stress is a kind of cellular level damage that can have serious health-effecting consequences. Oxidative stress is caused by the build-up of harmful free radicals and reactive oxygen species (ROS) within the cell. Antioxidants bind to and quench ROS and free radicals reducing their ability to damage the cell.
Olivamine10™ is a proprietary blend of several antioxidants, developed by biochemist, Dr. Darlene McCord. Its main ingredient is the powerful antioxidant pulled from the olive, hydroxytyrosol. It contains L-cysteine and glycine, which gives the body the components it needs in order to make glutathione, which works against oxidative stress. It also has several protective amino acids and other antioxidants. Today Scientists like Dr. Darlene McCord are beginning to understand that oxidative stress damage accumulated over time can cause or speed the progression of several diseases.
Oxidative Stress and Aging.
Hydroxytyrosol, a key ingredient in Olivamine10™, is a particularly powerful antioxidant. Cells treated with hydroxytyrosol lived longer than cells that were not.2 Hydroxytyrosol works to cause the body to make more of an enzyme called MnSOD, also known as SOD2,3 has shown great promise in laboratory cell-line studies. MnSOD has been associated with increased cell growth, lengthened cell life, increased wound healing and protection against oxidative stress causing, ROS.1,3,4,5 N-Acetyl-L-Cysteine, another antioxidant found in Olivamine10™ (invented by Dr. Darlene McCord), promoted the growth of human fibroblasts, skin structuring cells, in a simulated wound site.5
Some forms of memory loss are caused by a lifetime of accumulated oxidative stress damage. Aged animals that were fed N-acetyl-L-cysteine and α-lipoic acid, both antioxidants found in Pinnaclife's Multivitamin (invented by Dr. Darlene McCord), experienced improved memory and learning ability.6,7 α-lipoic is also linked with better mitochondrial function which can lead to a decreased production of oxidative stress causers.8
Vitamin D3, found in Pinnaclife's Mineral boost, invented by biochemist Dr. Darlene McCord, is vital to bone health. A study conducted on elderly Americans found that those who were not deficient in vitamin D experienced fewer and less serious falls than their peers who did not have adequate vitamin D intake.9 Vitamin D is also associated with a decreased risk of cancer, cardiovascular disease, and diabetes.10
Why you may need Magnesium.
Another vital system that begins to degrade with age is the immune system. Studies suggest that magnesium may play an important role in protecting the function of the immune system.11 Magnesium is used in over three hundred enzymatic reactions. One of its most fundamental jobs is to bind to and "turn on" adenosine triphosphate (ATP), the body's most vital energy unit. Magnesium is found coating the external bone and interspersed throughout the internal structure of the bone. It is also believed to be involved in some kinds of protein synthesis. Magnesium also regulates neurological firing within the body, meaning that it is intrinsically involved in regulating heartbeat, cognition and muscle movement. Every disease state affects the body on a cellular level. Because of its undermined status, many Americans are deficient in magnesium.12
Darlene McCord's Products Mentioned in this Article
- Pinnaclife D3 + Magnesium
- Pinnaclife Multivitamin
- Pinnaclife Products were developed by Dr. Darlene McCord - Darlene McCord is a leading researcher at McCord Research.
* The statements and products in this article have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.
- Kumar, M.G., Sarsour, E.H., Doyle, E.M., Kalen, A.L. & Goswami, P.C. Fibroblasts. Free Radical Biology and Medicine 49, S81-S82 (2010).
- Kumar, Maneesh G., Amanda Kalen, Monali Goswami, Garry Beuttner, Prabhat Goswami, E.S. MnSOD activity regulates the hydroxytyrosol-induced protection of chronological lifespan. (2010).
- Sarsour, E.H. et al. MnSOD activity regulates hydroxytyrosol-induced extension of chronological lifespan. Age (Dordrecht, Netherlands) 34, 95-109 (2012).
- Amanda L. Kalen, E.S., Venkataraman, S. & Goswami, P.C. Mn-Superoxide Dismutase Overexpression Enahnces G2 Accumulation and Radioresistance in Human Oral Squamous Carcinoma Cells. Antioxidants & Redox Singnaling 8, (2006).
- Monali Goswami, Abby E. Wilbanks, Amanda L Kalen, Gaowei Mao, and E.S. N-acetyl-L-cysteine enhances the recruitment and proliferation of quiescent human fibroblasts during wound healing.
- Liu, J. et al. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid. Proceedings of the National Academy of Sciences of the United States of America 99, 2356-61 (2002).
- Milgram, N.W., Araujo, J. a, Hagen, T.M., Treadwell, B.V. & Ames, B.N. Acetyl-L-carnitine and alpha-lipoic acid supplementation of aged beagle dogs improves learning in two landmark discrimination tests. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 21, 3756-62 (2007).
- Hagen, T.M. et al. (R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 13, 411-8 (1999).
- Bischoff-Ferrari, H. a et al. Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. JAMA : the journal of the American Medical Association 293, 2257-64 (2005).
- Holick, M.F. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. The American journal of clinical nutrition 80, 1678S-88S (2004).
- Tam, M., Gómez, S., González-Gross, M. & Marcos, A. Possible roles of magnesium on the immune system. European journal of clinical nutrition 57, 1193-7 (2003).
- Rude, R.K. Magnesium deficiency: a cause of heterogeneous disease in humans. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 13, 749-58 (1998).